HPLC Demo Sheet
Bayesian Optimisation for HPLC Method Development in Google Sheets
No Code, Just Results!
HPLC method development can take months.
Active Learning accelerate the process.
Bayesian Optimisation has been shown to generate optimal chromatograms in as few as 9 experiments! (Dixon et al., 2024).
Learn how to optimise HPLC method development in minutes using Matterhorn Studio's free Google Sheets™ Plug-In — no coding experience needed, no complex software installation!
In this step-by-step tutorial, Isla shows you how to:
Install the plug-in effortlessly
Run Bayesian Optimisation on real HPLC data
Get AI-powered experiment recommendations
Bayesian Optimisation for HPLC Method Development: Case Studies
Bayesian Optimisation (BO) excelled in data efficiency for LC method development.
BO outperformed other algorithms in real-measurement (wet) optimisation, even surpassing grid search in some cases.
Optimal HPLC conditions were found in as few as 9–13 experiments, significantly reducing development time.
Bayesian Optimisation method (BO) method outperformed traditional optimisation techniques like DoE and linear solvent strength models.
